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Takeshi Okanoue Selected Research

Collagen Type IV (Type IV Collagen)

9/2021Efficacy and safety of apararenone (MT-3995) in patients with nonalcoholic steatohepatitis: A randomized controlled study.
3/2021A novel rapid immunoassay of serum type IV collagen 7S for the diagnosis of fibrosis stage of nonalcoholic fatty liver diseases.
1/2021Type IV Collagen 7S Is the Most Accurate Test For Identifying Advanced Fibrosis in NAFLD With Type 2 Diabetes.
6/2020Epidemiology: Pathogenesis, and Diagnostic Strategy of Diabetic Liver Disease in Japan.
1/2020Diagnostic accuracy of combined biomarker measurements and vibration-controlled transient elastography (VCTE) for predicting fibrosis stage of non-alcoholic fatty liver disease.
1/2018A simple scoring system using type IV collagen 7S and aspartate aminotransferase for diagnosing nonalcoholic steatohepatitis and related fibrosis.
8/2017Assessment of transient elastography in Japanese patients with non-alcoholic fatty liver disease.
2/2017Classification of patients with non-alcoholic fatty liver disease using rapid immunoassay of serum type IV collagen compared with liver histology and other fibrosis markers.
5/2016[Present State of Non-B Non-C Liver Disease-and Its Monitoring.]
2/2011A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease.
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Takeshi Okanoue Research Topics

Disease

53Fibrosis (Cirrhosis)
01/2022 - 01/2003
51Non-alcoholic Fatty Liver Disease
08/2022 - 01/2003
32Hepatocellular Carcinoma (Hepatoma)
02/2022 - 02/2002
29Neoplasms (Cancer)
02/2022 - 02/2002
29Chronic Hepatitis C
03/2020 - 05/2002
19Infections
08/2020 - 08/2003
18Liver Cirrhosis (Hepatic Cirrhosis)
08/2022 - 02/2002
13Alcoholic Fatty Liver
02/2022 - 03/2009
13Fatty Liver
01/2022 - 01/2003
13Chronic Hepatitis B
06/2018 - 08/2002
12Insulin Resistance
01/2022 - 08/2003
12Inflammation (Inflammations)
11/2020 - 10/2003
8Hepatitis
04/2022 - 02/2004
6Body Weight (Weight, Body)
01/2022 - 03/2006
6Liver Diseases (Liver Disease)
01/2017 - 08/2002
6Hepatitis C
08/2014 - 09/2004
6Colitis
12/2008 - 03/2004
5Stomach Neoplasms (Stomach Cancer)
03/2021 - 11/2003
5Chronic Hepatitis (Chronic Active Hepatitis)
01/2010 - 08/2002
5Neoplasm Metastasis (Metastasis)
01/2007 - 01/2003
5Lymphoma (Lymphomas)
02/2006 - 09/2002
4Iron Overload
01/2013 - 08/2003
4Hepatitis B
04/2010 - 07/2005
4Colonic Neoplasms (Colon Cancer)
01/2007 - 01/2003
4Reperfusion Injury
04/2006 - 01/2004
4Ischemia
03/2006 - 01/2004
4Non-Hodgkin Lymphoma (Lymphosarcoma)
07/2005 - 03/2004
4Diarrhea
05/2005 - 03/2004
3Liver Neoplasms (Liver Cancer)
03/2021 - 05/2016
3Type 2 Diabetes Mellitus (MODY)
01/2021 - 01/2018
3Disease Progression
01/2021 - 05/2013
3Necrosis
02/2015 - 02/2004
3Fever (Fevers)
12/2006 - 03/2004
3Carcinoma (Carcinomatosis)
09/2005 - 07/2004
3Hemorrhage
07/2005 - 01/2004

Drug/Important Bio-Agent (IBA)

21Proteins (Proteins, Gene)FDA Link
12/2021 - 02/2004
19InterferonsIBA
11/2015 - 05/2002
15Antiviral Agents (Antivirals)IBA
12/2020 - 02/2002
15Ribavirin (Virazole)FDA LinkGeneric
05/2015 - 07/2004
14Alanine Transaminase (SGPT)IBA
11/2020 - 08/2003
12Biomarkers (Surrogate Marker)IBA
08/2022 - 05/2004
12Transaminases (Aminotransferases)IBA
12/2021 - 08/2003
11Collagen Type IV (Type IV Collagen)IBA
09/2021 - 04/2010
11DNA (Deoxyribonucleic Acid)IBA
10/2010 - 11/2003
10Messenger RNA (mRNA)IBA
03/2021 - 12/2002
10IronIBA
01/2013 - 06/2004
10Lamivudine (Epivir)FDA Link
09/2009 - 08/2002
9Pharmaceutical PreparationsIBA
11/2020 - 01/2006
8Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021 - 01/2010
8EnzymesIBA
12/2020 - 09/2004
7Biological ProductsIBA
12/2021 - 12/2004
6Fatty Acids (Saturated Fatty Acids)IBA
01/2022 - 04/2009
6Glucose (Dextrose)FDA LinkGeneric
01/2021 - 05/2011
6Hemoglobins (Hemoglobin)IBA
01/2021 - 05/2004
6AntigensIBA
05/2016 - 08/2002
6Reactive Oxygen Species (Oxygen Radicals)IBA
09/2010 - 07/2005
5selonsertibIBA
01/2022 - 11/2019
5Interleukin-6 (Interleukin 6)IBA
02/2015 - 08/2004
5Ferritins (Ferritin)IBA
01/2013 - 08/2003
5Peroxidase (Myeloperoxidase)IBA
08/2006 - 05/2004
5Thiobarbituric Acid Reactive SubstancesIBA
03/2006 - 05/2004
5CytokinesIBA
10/2005 - 05/2004
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2005 - 08/2002
4Phospholipases (Phospholipase)IBA
12/2021 - 08/2015
4Vitamin EFDA LinkGeneric
12/2021 - 01/2006
4Insulin (Novolin)FDA Link
01/2021 - 01/2011
4Peroxisome Proliferator-Activated Receptors (PPAR)IBA
12/2020 - 09/2010
4acarboxyprothrombin (PIVKA)IBA
08/2020 - 11/2004
4LDL CholesterolIBA
06/2020 - 12/2010
4RNA (Ribonucleic Acid)IBA
08/2014 - 09/2006
4Hepatitis B Surface Antigens (HBsAg)FDA Link
04/2013 - 02/2004
4OligonucleotidesIBA
10/2010 - 02/2009
4ThioredoxinsIBA
04/2009 - 01/2003
4Anti-Bacterial Agents (Antibiotics)IBA
12/2006 - 03/2004
3Immunoglobulin M (IgM)IBA
02/2022 - 12/2006
3alpha-Fetoproteins (alpha-Fetoprotein)IBA
02/2022 - 02/2002
3Aspartic Acid (Aspartate)FDA Link
01/2021 - 08/2002
3gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
01/2021 - 01/2010
3Amino AcidsFDA Link
01/2021 - 12/2010
3semaglutideIBA
01/2021 - 06/2020
3Serum AlbuminIBA
11/2020 - 07/2005
3Sodium-Glucose Transport ProteinsIBA
07/2020 - 02/2020
3Sodium-Glucose Transporter 2 InhibitorsIBA
07/2020 - 01/2018
3Glucagon-Like Peptide 1 (GLP 1)IBA
07/2020 - 03/2020
3oxidized low density lipoproteinIBA
06/2020 - 01/2011
3Hepatitis B e AntigensIBA
09/2016 - 08/2006
3SimeprevirIBA
05/2015 - 05/2014
3Triglycerides (Triacylglycerol)IBA
11/2014 - 01/2010
3Oxidants (Oxidizing Agents)IBA
02/2013 - 08/2010
3nasIBA
01/2011 - 04/2010
3NucleosidesIBA
04/2010 - 06/2009
3entecavirFDA Link
01/2010 - 06/2009
3PPAR alphaIBA
04/2009 - 11/2004
3Rituximab (Mabthera)FDA Link
12/2008 - 03/2005
3Free RadicalsIBA
03/2006 - 10/2005
3Oxygen (Dioxygen)IBA
03/2006 - 10/2005

Therapy/Procedure

53Therapeutics
04/2022 - 02/2002
12Drug Therapy (Chemotherapy)
03/2021 - 03/2004
5Aftercare (After-Treatment)
02/2021 - 10/2004
4Liver Transplantation
12/2021 - 11/2019